ICSI Center

Molecular Genetics Research Laboratory for Male Infertility / Advanced Micromanipulation Research Laboratory on Mammalian Gametes

 

Our field of interest is to device and execute research projects in reproductive biology. The main focus is on designing and carrying out research projects on the physiology of human gametes, spermatozoa, and oocytes in order to understand their maturation and interaction. Other fields of interest are the genetic basis responsible for spermatogenesis and to explore techniques for assessment of aneuploidy of eggs and sperm. Systematically device and organize follow-up studies to investigate the wellbeing of children born from assisted reproductive technologies (ART), IVF, ICSI, and those resulting from cryopreservation. Investigate methods to enhance the efficiency of cryopreservation procedures of human eggs.

American Society for Reproductive Medicine Annual Meeting 2017


A Thorough Genetic Assessment on the Aging Male Gamete

Stephanie Cheung, Zev Rosenwaks, and Gianiero D. Palermo


Adopting Sperm Chromatin Fragmentation to Steer Toward the Appropriate ART Treatment

Alessandra Parrella, Stephen Chow, Nigel Pereira, Marc Goldstein, Zev Rosenwaks, and Gianpiero D. Palermo


Genetic Screening by Sequencing Technology to Predict Embryo Developmental Competence of the Male Gamete

Stephanie Cheung, Zev Rosenwaks, and Gianpiero D. Palermo


Proportional Oocyte Nuclear Maturation in Relation to ICSI Outcome

Alessandra Parrella, Stephen Chow, Stephanie Cheung, Nigel Pereira, Zev Rosenwaks, and Gianpiero D. Palermo


Sperm Source Influences the Extent of DNA Fragmentation and Reproductive Outcome

Alessandra Parrella, Claire O'Neill, Stephen Chow, Marc Goldstein, Zev Rosenwaks, and Gianpiero D. Palermo


Screening for Germ Cells in Surgical Specimen That Fail to Yield Spermatozoa

Claire O'Neill, Mohamad Irani, Alessandra Parrella, Zev Rosenwaks, and Gianpiero D. Palermo


Revisiting Aneuploidy Characteristics of Surgically Retrieved Spermatozoa by DNA Sequencing (NGS)

Stephanie Cheung, Phillip Xie, Zev Rosenwaks, and Gianpiero D. Palermo


Determining Embryo Developmental Competence by Measuring Expressivity of the Paternal Genome

Nigel Pereira, Stephanie Cheung, Alessandra Parrella, Claire O'Neill, Nora Nikprelevic, Zev Rosenwaks, and Gianpiero D. Palermo


Investigating the Role of Sperm-Specific RNA to Screen Men with Unexplained Infertility

Nigel Pereira, Stephanie Cheung, Alessandra Parrella, Claire O'Neill, Nora Nikprelevic, Zev Rosenwaks, and Gianpiero D. Palermo


The Impact of Maternal Age at Retrieval on the Implantation Rate of Euploid Blastocysts

Mohamad Irani, Claire O'Neill, Gianpiero D. Palermo, Vinay Gunnala, Kangpu Xu, Nikica Zaninovic, and Zev Rosenwaks


The Impact of Semen Parameters Considering the Number of Dominant Follicles and Endometrial Thickness on the Outcome of Intrauterine Insemination Following Superovulation with Clomiphene Citrate

Mohamad Irani, Vivian Lu, Stephen Chow, Derek Keating, Simone Elder, Zev Rosenwaks, and Gianpiero D. Palermo


A Simple Method to Generate Germ Cells from Male Embryonic Stem Cells

Mohamad Irani, Vivian Lu, Alessandra Parrella, Stephen Chow, Brandon Chin, Claire O'Neill, Stephanie Cheung, Zev Rosenwaks, and Gianpiero D. Palermo


Embryonic Stem Cell Lines Derived from Somatic Cell Nuclear Transferred Oocytes Fertilizing With Sperm

Duancheng Wen, Stephen Chow, Stephanie Cheung, Alessandra Parrella, Gianpiero D. Palermo, and Zev Rosenwaks